The idea of Depression Lab is to seek out the most promising things for tackling depression, road-test them and then find ways to implement the useful ones.

Findings are recorded on the experiments page, whilst discussion of promising things can be found on the blog.

For an introduction, see Depression Lab Guide to Recovering from Depression – the basics



The stuff on this website is informed by the research literature, and based on experience and common sense. It should in no way be viewed as a substitute for advice from your GP.

NHS advice is to seek help from your GP if you experience symptoms of depression for most of the day, every day for more than two weeks. It is especially important to speak to your GP if you experience:

  • symptoms of depression that are not improving
  • your mood affects your work, other interests, and relationships with your family and friends
  • thoughts of suicide or self-harm

Contact the Samaritans if you feel suicidal: call 08457 90 90 90 or email – 24 hours a day


Depression Lab has no particular axe to grind – be it psychiatry, psychology, medicine, alternative therapy, neurobiology, whatever. It’s about safe, do-able things that improve mood and mental health.

Libby Ranzetta started recording her research and experiments here in 2014, having decided to get on top of her lifelong depression and associated problems through a determined programme of trial and error.

batgirl and raisin (Copy)I have suffered from depression all my life. Sometimes it is debilitating, sometimes just mildly miserable.

In 2010, after a breakdown, I could no longer work. Cognitive Behavioural Therapy (CBT) was helpful, as were antidepressants, and getting a dog, and eliminating the stress of work, but the depression never went far away.

Three years later, still not working, and feeling useless and hopeless, things looked fairly desperate. I was wasting my time and my life, resigned to being depressed forever and hoping forever wouldn’t last too long.

When the young daughter of a close friend was diagnosed with depression, I asked what I could do to help. “Be a good role model of someone with depression” my friend said.  It was the spark I needed to start fighting back.

Since then I have worked hard to do all the right things as far as possible, and feel much better. I am enjoying life at last, and am happy to be alive.

But I want to continue the journey, and to understand how and why positive change happens for me and for others.  I want to be a good role model. If Depression Lab helps you feel better, that’s brilliant.

Libby lives in Suffolk in the east of England with her (black) dog Raisin Dettra, her trombone, and an assortment of rescue bats in various stages of rehabilitation. She still has some bad days; the work to understand why and what to do about it continues.